| Acronym | Definition |
|---|
| LEM | Low End Mac |
| LEM | Luis Eduardo Magalhaes (Brazilian city) |
| LEM | Lunar Excursion Module |
| LEM | Link Error Monitor |
| LEM | Line Extender Module |
| LEM | Local Emergency Management |
| LEM | Licomp Empik Multimedia (Poland) |
| LEM | Location Efficient Mortgage |
| LEM | Learnable Evolution Model (artificial intelligence) |
| LEM | Law Enforcement Memorial (license plates; various locations) |
| LEM | Labor, Equipment, Materials (various companies) |
| LEM | Large Emerging Market |
| LEM | Lay Eucharistic Minister |
| LEM | Life Extension Magazine (Life Extension Foundation) |
| LEM | Language Extension Module |
| LEM | Law Enforcement Manual |
| LEM | Logistics Element Manager |
| LEM | Linear Electric Motor |
| LEM | Losing E-Mail |
| LEM | Law of Excluded Middle |
| LEM | Lyophilized Extract of Medlar |
| LEM | Licenciado En Mercadotecnia (Mexico) |
| LEM | Lateral Eye Movement (neuro-linguistic programming) |
| LEM | Local Effect Model |
| LEM | Lower Equipment Module (US NASA) |
| LEM | Live from Earth and Mars (educational project; also seen as LFEM) |
| LEM | Laboratory for Energy and Materials (cycles) |
| LEM | Living Eck Master (cult) |
| LEM | Launch Escape Monitor |
| LEM | Light Equipment Maintenance |
| LEM | Light Emission Microscopy / Microscope |
| LEM | Local Event Manager |
| LEM | Local Equipment Manager |
| LEM | Louisville Energy Marketing |