| Acronym | Definition |
|---|
| LME | London Metal Exchange (UK) |
| LME | Loi de Modernisation de l'Economie (French: Economy Modernization Act) |
| LME | Limited Maintenence Electrician |
| LME | Let Me Explain |
| LME | Large Marine Ecosystem |
| LME | Liability Management Exercise (finance) |
| LME | Local Management Entity |
| LME | Liquid Malt Extract |
| LME | Layer Management Entity |
| LME | Licensed Master Esthetician (dermatology) |
| LME | Liquid Metal Embrittlement |
| LME | Lightweight Maintenance Enclosure |
| LME | Labor, Material, Equipment (goods measurement) |
| LME | Lethal Military Equipment |
| LME | Local Multiplier Effect (finance) |
| LME | Large Memory-Enabled (Microsoft) |
| LME | Line Monitoring Equipment |
| LME | Lepidoptera of Middle East |
| LME | Last Man on Earth (movie) |
| LME | Liquid Motion in a Rotating Tank Experiment |
| LME | Linkage Message Exchange |
| LME | Line Module Equipment |
| LME | Liquid Management Experiment |
| LME | Laboratoire de Modélisation Environnementale (French: Environmental Modeling Laboratory) |
| LME | Lower Maintenance Expense |
| LME | Leaky-Mode Excitation |
| LME | Large Modern Ecotype |
| LME | Lloyd's Mirror Effect |
| LME | Least Mean Entropy |
| LME | Legion Medal of Excellence (The Royal Canadian Legion) |
| LME | Lunar Module Engine |
| LME | Logistics MANPRINT Evaluation |