| Acronym | Definition |
|---|
| MCAS | Massachusetts Comprehensive Assessment System |
| MCAS | Marine Corps Air Station |
| MCAS | Maneuvering Characteristics Augmentation System (automated aviation safety) |
| MCAS | Matrícula Consular de Alta Seguridad (Spansh: High Security Consular Registration) |
| MCAS | Microsoft Certified Application Specialist (Microsoft) |
| MCAS | Microsoft Certified Application Specialist |
| MCAS | Michigan City Area Schools (Michigan City, Indiana) |
| MCAS | Massachusetts Child Abuse System (standardized testing) |
| MCAS | Mediterranean Center for Arts and Sciences |
| MCAS | Mobile Servicing System (MSS) Common Attach System |
| MCAS | Mississippi Coast Audubon Society |
| MCAS | Midair Collision Avoidance System |
| MCAS | Mission Capability Assessment System |
| MCAS | Micro Communications and Avionics System |
| MCAS | Multispectral Collection & Analysis System |
| MCAS | Member of the Chinese Academy of Sciences |