| Acronym | Definition |
|---|
| MESA | Middle East Studies Association |
| MESA | Middle East/South Asia (education; also seen as MESEA) |
| MESA | Mathematics, Engineering, Science, Achievement |
| MESA | Multi-Ethnic Study of Atherosclerosis |
| MESA | Mobile Emergency and Safety Applications |
| MESA | Modular Equipment Storage Assembly |
| MESA | Mapleton Expeditionary School of the Arts (Colorado) |
| MESA | Moving to End Sexual Assault |
| MESA | Methyl Salicylate |
| MESA | Michigan Employment Security Act |
| MESA | Maximum Entropy Spectral Analysis |
| MESA | Meta Email Search Agent (meta search for email addresses) |
| MESA | Multinational Exchange for Sustainable Agriculture (Oakland, CA) |
| MESA | Mining Enforcement and Safety Administration |
| MESA | Maintenance Engineering Society of Australia |
| MESA | Mobility for Emergency and Safety Applications |
| MESA | Mathematics and Science Achievement (various organizations) |
| MESA | Manufacturing Execution Systems Association |
| MESA | Modular Equipment Stowage Assembly (Apollo Program) |
| MESA | Most Environmentally Sensitive Area (various locations) |
| MESA | Mathematics Education Student Association |
| MESA | Mobile Enhanced Situational Awareness Network |
| MESA | Michigan Employment Security Agency |
| MESA | Maryhaven Exploring Sober Alternatives (Ohio) |
| MESA | Manufacturing Enterprise Solutions Association International (Chandler, AZ) |
| MESA | Managing Effective Student Assessment (UK) |
| MESA | Magnuson Environmental Stewardship Alliance (Magnuson Park; Seattle, WA) |
| MESA | Modified Exclusive Shared Invalid (MESI states of cache memory) |
| MESA | Missile Engagement Simulation Arena |
| MESA | Miniature Electrostatic Accelerometer |
| MESA | Marshall Engineers and Scientists Association |
| MESA | MHI (Mitsubishi Heavy Industries) Equipment and Services Africa (Senegal) |
| MESA | Micro-Surgical Epididymal Sperm Aspiration |
| MESA | Microsystems Engineering Sciences Applications |
| MESA | Management Education Services Associates |
| MESA | Madeira Energia SA (Portuguese: Wood Energy; Brazilian business consortium) |
| MESA | Maintenance Engineering Support Analysis |
| MESA | Minimum Essential Support Analysis |
| MESA | Medical Epidemiology and Social Aspects of Aging (questionnaire) |