LOCO
| Acronym | Definition |
|---|---|
| LOCO | Locomotive (mining industry) |
| LOCO | Low Cost |
| LOCO | Loudoun County, Virginia (nickname) |
| LOCO | Land of Chaos Online (game) |
| LOCO | Layered Organization in the Coastal Ocean |
| LOCO | Ludlow Orchard Community Organization (New York) |
| LOCO | LOw COmplexity LOssless COmpression for Images |