| Acronym | Definition |
|---|
| LOD | Lord of Destruction (Diablo 2 game expansion) |
| LOD | Limit of Detection |
| LOD | Legacy of Darkness (game) |
| LOD | Lodi (Amtrak station code; Lodi, CA) |
| LOD | Level of Detail |
| LOD | Level of Development |
| LOD | Legion Of Doom |
| LOD | Line of Duty |
| LOD | Legend of Drizzt (gaming) |
| LOD | Legend of Dragoon (Sony role playing game) |
| LOD | Look of Disapproval |
| LOD | List of Documents (various organizations) |
| LOD | Line of Defense |
| LOD | Logarithm of Odds (genetic linkage analysis) |
| LOD | Live on Demand |
| LOD | Link of the Day |
| LOD | Life of Desiigner (album) |
| LOD | Life or Death |
| LOD | Line of Departure |
| LOD | Living Organ Donor |
| LOD | Low Oxalate Diet |
| LOD | Limit of Disturbance |
| LOD | Luck of the Draw |
| LOD | Lift Off Distance (computer mouse) |
| LOD | Length on Deck |
| LOD | Letter of Direction |
| LOD | Lines of Drift |
| LOD | Load File |
| LOD | Length of Day |
| LOD | Live or Die (gaming clan) |
| LOD | Letter of Deficiency (various locations) |
| LOD | Lord of the Dragons (gaming) |
| LOD | Lords of Destruction |
| LOD | Line of Dance (counter-clockwise movement) |
| LOD | Loss on Drying (water and volatile substances lost from a sample when dried) |
| LOD | Loss-On-Drying |
| LOD | Letter of Delegation |
| LOD | League of Draven (gaming) |
| LOD | Linked Open Data (Semantic Web) |
| LOD | Level of Detection |
| LOD | Learning on Demand (education and training) |
| LOD | Loss Of Data |
| LOD | Lords of Dogtown (movie) |
| LOD | Letter of Destruction |
| LOD | Lightning on Demand (Brisbane, CA) |
| LOD | Lords of Darkness (gaming) |
| LOD | Load on Demand |
| LOD | Log of Odds (genetic linkage score) |
| LOD | Lords of Death (gaming clan) |
| LOD | Laparoscopic Ovarian Drilling |
| LOD | Large Organic Debris |
| LOD | Loks on Dope |
| LOD | Liberty or Death |
| LOD | Letter of Demand (of Payment) |
| LOD | Laid-Off Dad |
| LOD | Lines of Development |
| LOD | Land of Devastation (BBS role-playing game) |
| LOD | Low of Day (stock markets) |
| LOD | Level of Dependence |
| LOD | Leader-On-Duty (Target stores employee title) |
| LOD | Ladies of Distinction |
| LOD | lateral overflow drain |
| LOD | Lethal Overdose (band) |
| LOD | Last Order Date (sales) |
| LOD | Launch on Demand |
| LOD | Legion of the Damned (gaming group) |
| LOD | Loss of Down (football) |
| LOD | Lecture on Demand (academic curriculum) |
| LOD | Lords of Discipline |
| LOD | Life Over Death (band) |
| LOD | Launch Operations Directorate |
| LOD | Line of Demolition (construction) |
| LOD | Line Out Dock |
| LOD | Lëtzebuerger Online Dictionnaire |
| LOD | Leadership and Organizational Development |
| LOD | Legends of Darkness (gaming clan) |
| LOD | Leading-One Detector |
| LOD | Lease Outline Drawings |
| LOD | List of Drawings |
| LOD | Locally Optimum Detector |
| LOD | Low Overhead Driver |
| LOD | Look of Death |
| LOD | Landlord Outline Drawing |
| LOD | Last Opportunity Doctrine |
| LOD | Lease Option Document |
| LOD | Letter of Diagnosis |
| LOD | Linear Optimal Distribution |
| LOD | Live Off Disk (DVR buffer) |
| LOD | Lease Outline Diagram |