| Acronym | Definition |
|---|
| MESS | Messieurs |
| MESS | Managed E-Mail Surveillance Service |
| MESS | Multi-Emulator Super System (computer program that emulates early home computers and video games) |
| MESS | Mangled Extremity Severity Score |
| MESS | Ministry of Education, Science and Sport (Sweden) |
| MESS | Ministère de l'Enseignement Supérieur et de la Science |
| MESS | Messapic (linguistics) |
| MESS | Marvelous Explorations Through Science and Stories |
| MESS | Monash Engineering Students' Society (Australia) |
| MESS | Multi Engine Search Script |
| MESS | Model Evaluation Support System |
| MESS | Metal Sanayicileri Sendikasý (Turkish: Metal Industrialists' Union) |
| MESS | Maximum Effective Sonar Speed |
| MESS | Mesoscale and Severe Storms Computer System |
| MESS | Mechanical and Electrical Subsystem Simulator (Mariner IV mission) |
| MESS | Maintenance Engineering Support Services |
| MESS | Maintenance of Electronic Super Sonics |