| Acronym | Definition |
|---|
| MSU | Michigan State University |
| MSU | Morehead State University (Kentycky) |
| MSU | Montana State University |
| MSU | Mississippi State University |
| MSU | Minnesota State University |
| MSU | Montclair State University (Upper Montclair, NJ, USA) |
| MSU | Minot State University (North Dakota) |
| MSU | Missouri State University (formerly Southwest Missouri State University SMSU) |
| MSU | Midwestern State University (Wichita Falls, Texas) |
| MSU | Murray State University |
| MSU | Mountain State University (West Virginia) |
| MSU | Morgan State University (Baltimore, Maryland) |
| MSU | Moscow State University (Russian Federation) |
| MSU | Mahasarakham University (Thailand) |
| MSU | Maharaja Sayajirao University (India) |
| MSU | Management and Science University (Malaysia) |
| MSU | Maxxpro Survivability Upgrade (US Army) |
| MSU | Mayville State University (North Dakota) |
| MSU | McNeese State University |
| MSU | Mindanao State University |
| MSU | McNeese State University (Lake Charles, Louisiana) |
| MSU | Microwave Sounding Unit |
| MSU | Muslim Student Union |
| MSU | Marine Safety Unit |
| MSU | Marshal of the Soviet Union (Russia) |
| MSU | Microsoft University |
| MSU | Multiple Small Units (gaming) |
| MSU | Medical Support Unit (various organizations) |
| MSU | Mobile Stroke Unit (cardiology) |
| MSU | Mass Storage Unit |
| MSU | Management Support Unit |
| MSU | Making Stuff Up |
| MSU | Monosodium Urate |
| MSU | Mécanisme de Supervision Unique (French: Single Supervisory Mechanism; EU) |
| MSU | Memorial Student Union (various schools) |
| MSU | Memphis State University |
| MSU | Unit of Measure |
| MSU | Main System Unit (electronics) |
| MSU | Message Signal Unit |
| MSU | Mid-Stream Urine (sample) |
| MSU | Mobile Surgical Unit |
| MSU | Multinational Specialized Unit (NATO) |
| MSU | Maximum Security Unit (prison) |
| MSU | Mimar Sinan University |
| MSU | Major Subordinate Unit |
| MSU | Mobile Screening Unit (healthcare) |
| MSU | Medical Statistics Unit (various locations) |
| MSU | Maharaja Sayajirao University of Baroda (Gujarat, India; also seen as MSUB) |
| MSU | Millions of Service Units |
| MSU | Medium Secure Unit (psychiatric facility) |
| MSU | Make Something Up |
| MSU | Mu Sigma Upsilon (multicultural sorority) |
| MSU | McMaster Student Union |
| MSU | Mid-Stream Specimen of Urine (diagnostic) |
| MSU | Managed Service Upgrade (software) |
| MSU | Maseru, Lesotho - Maseru (Airport Code) |
| MSU | Modem Sharing Unit |
| MSU | Multi-Subscriber Unit |
| MSU | Medical Service Unit |
| MSU | Matrix Switching Unit (Paragon) |
| MSU | Microsoft Update Standalone Package for Windows Vista |
| MSU | Mushroom Society of Utah (Utah) |
| MSU | Memory Scheduling Unit |
| MSU | Modular Switching Unit |
| MSU | Media Server Unit |
| MSU | Metallic Service Unit |
| MSU | Message Storage Unit |
| MSU | Mine Search Unit |
| MSU | Morehead Sate University (Morehead, KY) |
| MSU | Management Station for Unix |
| MSU | Maintenance and Status Unit |
| MSU | Master Supervisory Unit (Alcatel) |
| MSU | Management Station for ULTRIX (DEC) |
| MSU | Microbacterial Subliminal Univalve (shellfish biology) |
| MSU | Modular Service Unit (telecommunications) |
| MSU | Message System Upgrade |
| MSU | Medium Size Unit (UK) |
| MSU | Million Statistical Unit |
| MSU | Mid-Shakedown Upkeep |