| Acronym | Definition |
|---|
| LOC | Library Of Congress |
| LOC | Lines Of Code (software development) |
| LOC | Line Of Credit |
| LOC | Level Of Consciousness (medical) |
| LOC | Location |
| LOC | Line of Control |
| LOC | Locate(ing) |
| LOC | Loss of Control |
| LOC | Locality |
| LOC | Letter Of Credit |
| LOC | Length of Cut (measurement) |
| LOC | Local Organizing Committee (various organizations) |
| LOC | Line of Coverage (insurance) |
| LOC | Line of Communications (US DoD) |
| LOC | Letter of Confirmation (various organizations) |
| LOC | Level of Care |
| LOC | Loss of Consciousness |
| LOC | Locative (vestigial Latin case) |
| LOC | League of Champions (various locations) |
| LOC | Lines of Communication |
| LOC | List of Contributors |
| LOC | Lemoyne-Owen College (Memphis, TN, USA) |
| LOC | Localizer (instrument flying) |
| LOC | Length-of-Curve (stress metric) |
| LOC | Lab On a Chip |
| LOC | Left of Center (Charlottesville, VA) |
| LOC | Local Operating Company |
| LOC | Learning outside the Classroom (various organizations) |
| LOC | Low Operating Cost |
| LOC | Level Of Concern |
| LOC | Lexus Owners Club (car club) |
| LOC | Life of Crime (game) |
| LOC | Lines of Code |
| LOC | Loop Online Control |
| LOC | Locate |
| LOC | Locus of Control |
| LOC | Lesbians of Color (various locations) |
| LOC | Land of Confusion |
| LOC | Low Organic Carbon |
| LOC | Leftover Crack (band) |
| LOC | Lost Opportunity Cost |
| LOC | Letter of Commendation |
| LOC | Letter of Compliance |
| LOC | Lateral Orbitofrontal Cortex |
| LOC | Loss of Cell |
| LOC | Loss of Cell (delineation; ATMF) |
| LOC | Letter Of Consent |
| LOC | Lord of Chaos (Wheel of Time; book 6) |
| LOC | Logic of Constraints |
| LOC | Lake Ontario Counties (Rochester, NY) |
| LOC | Lead On Chip |
| LOC | Limiting Oxidant Concentration |
| LOC | Loss of Containment |
| LOC | Logistics Operations Center |
| LOC | Loss of Continuity (Sprint-ATM) |
| LOC | Learning Opportunity Center (various locations) |
| LOC | League Online Community (National League of Cities) |
| LOC | Local Oversight Committee (Oak Ridge, Tennessee) |
| LOC | Loan Origination Center |
| LOC | Letter Of Counseling |
| LOC | Land of Chocolate (band) |
| LOC | Loop On-Line Control |
| LOC | Launch Operations Center |
| LOC | Line Out Converter |
| LOC | Loss of Carrier |
| LOC | Loss of Clock (DSC) |
| LOC | Limited Operational Capability |
| LOC | Large Optical Cavity |
| LOC | License of Occupation |
| LOC | LAN Operations Center |
| LOC | Labuan Online Community |
| LOC | Liquid Organic Cleaner (Amway) |
| LOC | Level of Operational Capability |
| LOC | Laxative of Choice |
| LOC | Lowest Outgoing Channel |
| LOC | Local Operator Console |
| LOC | Letter of notification of personnel Clearance |
| LOC | Oxygen Lance Cutting (welding) |
| LOC | Lunar Orbit Capture |
| LOC | London Open College |
| LOC | Loss of Channel (Cisco) |
| LOC | Letter Of Conditions |
| LOC | Left Outer Canthus |
| LOC | Lords of Crabula (gaming clan) |
| LOC | Lockout Chamber |
| LOC | Logical Output Channel |
| LOC | Lower Order Concern (writing) |
| LOC | Lynn Operations Center |
| LOC | Love of Crip |
| LOC | Life of Company |