| Acronym | Definition |
|---|
| MDD | Major Depressive Disorder |
| MDD | Maximum Daily Dose |
| MDD | Manic-Depressive Disorder (now called Bipolar Disorder) |
| MDD | Model-Driven Development (software engineering) |
| MDD | Medical Device Directive |
| MDD | Map and Driving Directions |
| MDD | Maximum Dry Density (construction) |
| MDD | Maryland-Delaware-DC (Washington, DC) |
| MDD | Marque de Distributeur (French: private brand) |
| MDD | Mate Demate Device (places Space Shuttle on/off 747 carrier aircraft) |
| MDD | Mal de Debarquement Syndrome (French: Sore Disembarkation Syndrome; vertigo) |
| MDD | Medical Devices and Diagnostics |
| MDD | Million Dollar Dream (record label) |
| MDD | Model Driven Development |
| MDD | Mine Detection Dog |
| MDD | Materiel Development Decision |
| MDD | Mineral Deposits Division (Geological Association of Canada) |
| MDD | Mirrored Drive Door (Apple Power Mac) |
| MDD | Metal Detection Device |
| MDD | Movement for Democracy and Development (Central African Republic) |
| MDD | Major Design Decision |
| MDD | MySQL Database Diagram (computing) |
| MDD | Meteorological Data Distribution |
| MDD | Maintenance Due Date |
| MDD | Management Division Director |
| MDD | Marca del Distribuidor (Spanish: Brand Distributor) |
| MDD | Movement for Direct Democracy (Prague, Czech Republic) |
| MDD | Model Device Driver |
| MDD | Merchant Defined Data |
| MDD | Multi-Dimensional Databases (computing) |
| MDD | Multiple-valued Decision Diagram (generalized version of Binary Decision Diagram) |
| MDD | Marketing and Distribution Devision (Premier Farnell; UK) |
| MDD | Matson, Driscoll & Damico, LLP |
| MDD | Melting Degree Days |
| MDD | Mission Description Document |
| MDD | Mechanical Dough Development |
| MDD | Multiple Differential Detection |
| MDD | Minimum Distance Decoding |
| MDD | Multi Domain Diffusion |
| MDD | Maintenance Data Documentation |
| MDD | Maine Driving Dynamics |
| MDD | MacDonald-Detweiler |
| MDD | Material Delivery Date |
| MDD | Mode Description Document |
| MDD | Material Data Document |