| Acronym | Definition |
|---|
| MDN | Ministère de la Défense Nationale (Canada) |
| MDN | Midland Daily News (Midland, MI, USA) |
| MDN | Mainichi Daily News (newspaper) |
| MDN | Meriden (Amtrak station code; Meriden, CT) |
| MDN | Minieres du Nord (Canadian mining company) |
| MDN | Major Device Number |
| MDN | Mail Delivery Notification |
| MDN | Multiple Domain Network |
| MDN | Mobile Directory Number |
| MDN | Multilingual Domain Name |
| MDN | Mobile Data Network |
| MDN | Message Disposition Notification |
| MDN | Mobile Directory Number (Cellular) |
| MDN | Message Disposition Notification (Cisco & RFC-2298) |
| MDN | Missouri Digital News |
| MDN | Ministerio de Defensa Nacional (Uruguay) |
| MDN | Mobile Device Number |
| MDN | Mercury Deposition Network (US EPA) |
| MDN | Marcos de Niza (Tempe, AZ high school) |
| MDN | Madison, Wisconsin (Airport Code) |
| MDN | Mdina (postal locality, Malta) |
| MDN | Managed Data Network (various companies) |
| MDN | Microsoft Developer Network (usually seen as MSDN) |
| MDN | Mozilla Developer Network (web development tools website) |
| MDN | Mobilisation pour le Développement National (French: Mobilization for National Development, Haiti) |
| MDN | Midwest Democracy Network |
| MDN | Macular Degeneration Network (eyes) |
| MDN | Medical Decisions Network (Charlottesville, Virginia) |
| MDN | Malware Delivery Network |
| MDN | Ministerio de la Defensa Nacional (Guatemala) |
| MDN | Music Discovery Network |
| MDN | Medisinsk Diagnostisk Nettverk (network of Scandinavian health personnel) |
| MDN | Meta Data Navigator (graphical user interface; Atmospheric Radiation Measurement; US Department of Energy) |
| MDN | Mystro Digital Navigator (Time Warner Cable DHCT client application) |
| MDN | Muslim Death Notices (website) |
| MDN | Multiple Directory Numbers |
| MDN | Media Distribution Network (Motorola) |
| MDN | MAC Distributor Network |
| MDN | Mutual Defense Network (CashWars game) |
| MDN | Manipal Dot Net (India) |
| MDN | MasterDarkNinja (gaming) |
| MDN | Macro Definition Notation (ASN.1) |
| MDN | Manufacturer's Drawing Number |
| MDN | More Developed Nations |
| MDN | Main Distribution Node (expandable communications facility) |
| MDN | Musicals Dot Net (website) |