| Acronym | Definition |
|---|
| MDSC | Meta Data Server Cluster |
| MDSC | Management Data Service Center |
| MDSC | Massachusetts Down Syndrome Congress (Melrose, MA) |
| MDSC | Modulated Differential Scanning Calorimetry |
| MDSC | Medical Science (various universities) |
| MDSC | Mood Disorders Society of Canada (est. 2001) |
| MDSC | Maui Dolphins Swim Club |
| MDSC | Muscle-Derived Stem Cell |
| MDSC | Mount Diablo Silverado Council (Boy Scouts of America) |
| MDSC | Multi-Dimensional Separation of Concerns (computer science) |
| MDSC | Myeloid Derived Suppressor Cell (tumor related) |
| MDSC | Metropolis of Detroit Summer Camp (Michigan) |
| MDSC | Multimedia Data Services Corporation (Hyde Park, UT) |
| MDSC | Metropolitan Detroit Ski and Recreation Council (Michigan) |
| MDSC | Missoula Developmental Service Corporation (Missoula, MT) |
| MDSC | Midwest Disc Sports Collection (Missouri) |
| MDSC | Maximum-Distance Separable Code |
| MDSC | Messenger Discovery Skin Creator |