| Acronym | Definition |
|---|
| NLE | Non Linear Editing (video editing) |
| NLE | Neonatal Lupus Erythematosus (disorder) |
| NLE | Natural Language Engineering (various organizations) |
| NLE | Network Leader Election |
| NLE | Non Linear Editing |
| NLE | National Level Exercise (US FEMA) |
| NLE | National Library for the Environment |
| NLE | National Library of Energy (US Department of Education) |
| NLE | National Library of Education |
| NLE | New Leader Essentials (boy scouting) |
| NLE | National Latin Exam |
| NLE | Non-Linear Effect |
| NLE | North Luzon Expressway (Philippines) |
| NLE | Not Less or Equal |
| NLE | Networked Learning Environment |
| NLE | NEC Laboratories Europe (est. 1994; various locations) |
| NLE | Niles, Michigan (Airport Code) |
| NLE | No Longer Employed |
| NLE | Normal Loss Expectancy (insurance) |
| NLE | Necrotizing Leukoencephalitis |
| NLE | National Level Enclave |
| NLE | Network-Layer Encryption (Cisco) |