PUFF
| Acronym | Definition |
|---|---|
| PUFF | Pulmonary Function in Flight (US NASA) |
| PUFF | People United for Families (various locations) |
| PUFF | Portland Ultimate Frisbee Federation (Portland, OR) |
| PUFF | Pakistan-USA Freedom Forum (political group) |
| PUFF | Pulsed Ultra High Flux |
| PUFF | Protestant Ulster Freedom Fighters (UK) |