| Acronym | Definition |
|---|
| MPK | Moorpark (Amtrak station code; Moorpark, CA) |
| MPK | Manual Prosedur Kerja (Malay: Work Procedure Manual) |
| MPK | Multi Processing Kernel |
| MPK | Multi Pack |
| MPK | Monterey Park (California) |
| MPK | Michael Patrick King (film production) |
| MPK | Marginal Product of Capital (economics) |
| MPK | Miejskie Przedsiebiorstwo Komunikacyjne (Polish transport company) |
| MPK | Multi Purpose Knife |
| MPK | methyl propyl ketone |
| MPK | Monster Player Kill (roleplaying game) |
| MPK | Ministerpräsidentenkonferenz (German: Prime Ministers' Conference) |
| MPK | Maine Pyar Kiya (Indian movie) |
| MPK | Message per Keystroke (protocol variant used with video routing equipment) |
| MPK | Mad Porno Krew |
| MPK | Milligrams per Kilograms (clinical trials and drug composition) |
| MPK | Missing Presumed Killed |
| MPK | Manpack |
| MPK | Mini Pop Kids |
| MPK | Multi-Hop Pairwise Key |
| MPK | Maintenance Parts Kit |
| MPK | Midgaard Portal Keep (Dark Age of Camelot MMORPG) |