| Acronym | Definition |
|---|
| OBR | Office for Budget Responsibility (UK) |
| OBR | Open Business Report |
| OBR | on Board Recorder |
| OBR | One Button Restore |
| OBR | Optical Balanced Receiver |
| OBR | One Button Recovery |
| OBR | Optical Braille Recognition |
| OBR | Object Browser |
| OBR | Oracle Business Rules |
| OBR | Optically Boosted Router |
| OBR | Ohio Board of Regents |
| OBR | Optical Backscatter Reflectometer |
| OBR | Overhead Bridge Restaurant (Malaysia) |
| OBR | Optimized Background Regimen (used in HIV treatment) |
| OBR | Official Baseball Rules |
| OBR | Ortsbeirat (German: Municipal Advisory Council) |
| OBR | Online Banking Report |
| OBR | Ole Buhl Racing (UK; motorsport electronics) |
| OBR | One Block Radius |
| OBR | Old British (linguistics) |
| OBR | Oscillatory Baffled Reactor (plug-flow chemical reactor for mixing combinations of solids/liquids/gases) |
| OBR | Oncology Business Review |
| OBR | Open Box Return |
| OBR | Outer Boot Ring |
| OBR | Optimized Battle Rifle (firearm) |
| OBR | Orleans Bulldog Regiment (Orleans, IN school band) |
| OBR | Office of Budget and Reports (US Navy) |
| OBR | Optimization-Based Recognition |
| OBR | Original Broadway Recording |
| OBR | Optional Benefit Rider (insurance) |
| OBR | Off But Registering |
| OBR | Office Building Research |
| OBR | Output between Regeneration (water treatment) |