| Acronym | Definition |
|---|
| OBS | Observation (Groundwater Modeling Systems) |
| OBS | Observer |
| OBS | Organization(al) Breakdown Structure |
| OBS | Open Broadcaster Software (live streaming software) |
| OBS | Observed |
| OBS | Obviously |
| OBS | Obsolete |
| OBS | Obstacle |
| OBS | Ocala Breeders Sales |
| OBS | Olympic Broadcasting Services (International Olympic Committee) |
| OBS | Olin Business School (Washington University; St. Louis, MO) |
| OBS | Obstruction (baseball) |
| OBS | Ocean Bottom Seismic |
| OBS | Orange Business Service (France Telecom) |
| OBS | Openbare Basisschool |
| OBS | Oita Broadcasting System (Japan) |
| OBS | Office of Biological Services (US FWS) |
| OBS | Object Script |
| OBS | Output Based Specification |
| OBS | Oracle Balance Scorecard |
| OBS | on Board Switching |
| OBS | On-Board System (US Air Force) |
| OBS | Optical Burst Switching (IEEE) |
| OBS | Orange Blossom Special |
| OBS | Organic Brain Syndrome |
| OBS | Off Balance Sheet |
| OBS | Ocean Bottom Seismometer |
| OBS | Océ Business Services (New York, NY) |
| OBS | Online Business Systems (Canada) |
| OBS | Outward Bound School |
| OBS | Office of Boating Safety (Canadian Coast Guard) |
| OBS | Online Banking Solutions (various locations) |
| OBS | Outward Bound Sabah (educational organization; Sabah, Malaysia) |
| OBS | Operation Black Swan (US DoD) |
| OBS | Omni Bearing Selector |
| OBS | Other Basic Sciences |
| OBS | Olbrich Botanical Society (Madison, WI) |
| OBS | Outward Bound Singapore |
| OBS | Out of the Box Search (software) |
| OBS | Outdoor Base Station (wireless networking solution) |
| OBS | Obstructive Bowel Syndrome |
| OBS | Open Bidding Service (Canada) |
| OBS | Orlando Ballet School (Florida, USA) |
| OBS | Old Black Spruce |
| OBS | On-Board Stability |
| OBS | Optical Back Scatter (class of turbidity sensors) |
| OBS | Osaka Bible Seminary (Japan) |
| OBS | Oily Bird Syndrome |
| OBS | On-Board Service |
| OBS | Out-of-Band Signaling |
| OBS | Oxford Biosignals Ltd |
| OBS | Online Billing Services (various companies) |
| OBS | Operational Bioinstrumentation System |
| OBS | Old Brown Sherry |
| OBS | old body style (automotive) |
| OBS | Okasan Business Service Co., Ltd. (Japan) |
| OBS | Operation Boat Smart |
| OBS | Optical Biopsy System |
| OBS | On-Board Switching |
| OBS | Obligation à Bons de Souscriptions |
| OBS | Off Bore Sight |
| OBS | Office Based Sales |
| OBS | OSIS Baseline System |
| OBS | On-Base Average and Slugging percentage (baseball statistic) |
| OBS | On Board Spares |
| OBS | Out of Balance Switch |