| Acronym | Definition |
|---|
| MPSC | Michigan Public Service Commission |
| MPSC | Moree Plains Shire Council (Australia) |
| MPSC | Missouri Public Service Commission |
| MPSC | Mississippi Public Service Commission |
| MPSC | Master Plan Steering Committee (various schools) |
| MPSC | Maryland Public Service Commission |
| MPSC | Multi Producer Single Consumer |
| MPSC | Mount Pleasant Swim Club (South Carolina) |
| MPSC | Microsoft Partner Solution Center |
| MPSC | Multi-Port Serial Card |
| MPSC | Maharashtra Public Service Commission |
| MPSC | Movimiento Popular Social Cristiano |
| MPSC | Motion Picture Screen Cartoonists (union) |
| MPSC | Multi Protocol Serial Controller |
| MPSC | Military Personnel Service Center |
| MPSC | Meet at Park Street Circle (University of Wisconsin - Madison) |
| MPSC | Minnesota Public Service Commission |
| MPSC | Mitchell Purchased Student Computer |