| Acronym | Definition |
|---|
| NOSC | Navy Operational Support Center |
| NOSC | Naval Ocean Systems Center (US Navy) |
| NOSC | Network Operations and Security Center |
| NOSC | National Obesity Surgery Centre (UK) |
| NOSC | Network Operations Security Center |
| NOSC | Neighborhood Open Space Coalition (New York City, New York) |
| NOSC | North Olympic Salmon Coalition (Hadlock, Washington) |
| NOSC | National Open Source Committee (National Open Source Enterprise) |
| NOSC | Naples Overseas Spouses' Club (Naples, Italy) |
| NOSC | NOAA Observing Systems Council |
| NOSC | National Outreach Scholarship Conference (various universities) |
| NOSC | New Orleans Swing Combo (Thierry Ulrich band; New Orleans, LA) |
| NOSC | No Scope (video games) |
| NOSC | Nagrak Organic SRI Center |
| NOSC | Navy On-Scene Commander |
| NOSC | Newport Officers' Spouses' Club (Rhode Island) |
| NOSC | Non Ordinary State of Consciousness |
| NOSC | National Open Source Center |
| NOSC | Network Operation and Support Center |
| NOSC | North Olmstead Sportsman's Club (Ohio) |
| NOSC | Navy Officer's Spouse Club |
| NOSC | Network Operational Sub-Committee (UK ITV network) |