| Acronym | Definition |
|---|
| NPU | Network Processor Unit |
| NPU | North Park University (Chicago, IL) |
| NPU | National Pedagogical University (various locations) |
| NPU | Network Processing Unit |
| NPU | Northwestern Polytechnic University (Fremont, CA) |
| NPU | Neighborhood Planning Unit |
| NPU | Net Protein Utilization |
| NPU | Negative Pressure Unit (air filtration) |
| NPU | Nippon Polyurethane (Japan) |
| NPU | Neo Productions Unlimited (gaming) |
| NPU | Nitrogen Purge Unit (US NASA) |
| NPU | Nomenclature Properties and Units |
| NPU | National Poisons Unit |
| NPU | National Police University (various locations) |
| NPU | Numeric Processing Unit (like FPU) |
| NPU | Natural Push Up |
| NPU | Nice Pick Up (gaming) |
| NPU | Noise Pick-Up |
| NPU | Nosocomial Pressure Ulcer |
| NPU | Naval Parachute Unit (US Navy) |
| NPU | Non-Published Number (telephone Industry) |
| NPU | Nice Parts Usage |
| NPU | Named Patient Use (pharmaceutical program) |