| Acronym | Definition |
|---|
| MSE | Mouse (computer) |
| MSE | Mean Square Error |
| MSE | Mean Squared Error |
| MSE | Microsoft Security Essentials (antivirus software) |
| MSE | Master of Science in Economics |
| MSE | Master of Science in Engineering |
| MSE | Materials Science & Engineering |
| MSE | Mechanically Stabilized Earth (retaining wall) |
| MSE | Master of Science in Education |
| MSE | Mental Status Examination |
| MSE | Manufacturing Systems Engineering |
| MSE | Master of Software Engineering |
| MSE | Maintenance Support Equipment |
| MSE | Manufacturing Support Equipment |
| MSE | Microelectronic Systems Education |
| MSE | Macedonian Stock Exchange |
| MSE | Medium Scale Enterprises |
| MSE | Mathematics Stack Exchange (website) |
| MSE | Moist Static Energy (climate model) |
| MSE | Meta Search Engine |
| MSE | Master of Special Education (various schools) |
| MSE | Madras Stock Exchange (India) |
| MSE | Management Strategy Evaluation (model) |
| MSE | Managed Services Engine (software) |
| MSE | Mechanical Science and Engineering (various locations) |
| MSE | Modello Sociale Europeo (Italian: European Social Model) |
| MSE | Middle School Education (various locations) |
| MSE | My Sentiments Exactly |
| MSE | Microsoft Excel |
| MSE | Microsoft Scripting Engine |
| MSE | Message Stream Encryption |
| MSE | Mobile Subscriber Equipment |
| MSE | Measurement System Engineering (Texas Christian University) |
| MSE | Mobility Services Engine (Cisco Systems, Inc.) |
| MSE | Medical Screening Examination |
| MSE | Mechanical Specific Energy |
| MSE | Microsoft Script Editor |
| MSE | Multimedia Software Engineering |
| MSE | Micro- and Small- Enterprise |
| MSE | Middle School East (various locations) |
| MSE | Medical Screening Exam |
| MSE | Master of Science in Epidemiology (various schools) |
| MSE | Marine South East (UK) |
| MSE | Missile Segment Enhancement |
| MSE | Milton S. Eisenhower Symposium (lecture series; Johns Hopkins University; Maryland) |
| MSE | Mongolian Stock Exchange |
| MSE | Medical Support Equipment |
| MSE | Mid-Sized Enterprise |
| MSE | Major Subordinate Element |
| MSE | Mustafa Sultan Enterprises (joint venture; various locations) |
| MSE | Mediterranean Seafood Exhibition (trade show) |
| MSE | Millennium Science and Engineering |
| MSE | Maintenance Scheduling Effectiveness |
| MSE | Montreal Stock Exchange |
| MSE | Middle School Endorsement (teaching certification) |
| MSE | Mission Support Element |
| MSE | Microelectronics Systems Education (Conference) |
| MSE | Master Sign Electrician |
| MSE | Multi-Service Edge (switch) |
| MSE | Mechanical Support Equipment (Australia) |
| MSE | Mercury Surface Element |
| MSE | Muscular Strength and Endurance |
| MSE | International Workshop on Multimedia Software Engineering |
| MSE | Maritime Security Expo (trade show) |
| MSE | Medical Student Elective (various organizations) |
| MSE | Museum of Systematics and Ecology (UC Santa Barbara) |
| MSE | Machine Shop Estimating (Micro Estimating Systems, Inc.) |
| MSE | Measurement System Evaluation |
| MSE | Multiphase Systems Engineering |
| MSE | Mobile Station Equipment (GSM) |
| MSE | Modulated Scattering Element |
| MSE | Multiple Subscriber Equipment |
| MSE | Molten Salt Extraction |
| MSE | Moscow School of Economics |
| MSE | Multiple Spin Echoes |
| MSE | Mississippi Export Railroad Company |
| MSE | Medium-Sized Entity (Pakistan) |
| MSE | Micro-Solutions Engineering (Newtown, CT) |
| MSE | Mathematics, Science and Education |
| MSE | Multiple Stable Equilibria |
| MSE | Mission Systems Engineer |
| MSE | Module Substitution Error |
| MSE | Mastering Scientific Evidence (in DUI/DWI Cases) |
| MSE | Multiple Simultaneous Engagements (Missile Defense Agency) |
| MSE | Motorcycle Safety Equipment |
| MSE | Maintenance Sub-Entities (ITU-T) |
| MSE | Mobile Service Equipment |
| MSE | Manually Signed English |
| MSE | Main Staff Element |
| MSE | Missile Support Element |
| MSE | Mode Selecting Element |
| MSE | Materiel Status Evaluation |
| MSE | Mission Sponsor Equipment |
| MSE | Manned Spacecraft Engineer |
| MSE | Military Standard Exception |
| MSE | Market Specific Expert |
| MSE | Marketing Support Engineering (Sprint) |
| MSE | Military Services Expense |
| MSE | Multiple Symbol Estimation |
| MSE | Material Safety Experiments |
| MSE | Multiple Simulation Exercise |
| MSE | Maximum State of Efficiency (computer engineering) |
| MSE | Member of Society of Engineers (UK) |
| MSE | Mayurbhanj School of Engineering (India) |
| MSE | Moldava Stock Exchange |
| MSE | Mission Scheduling Effectiveness (US Air Force) |
| MSE | Modular Software Expertise (Thailand) |