| Acronym | Definition |
|---|
| MSIS | Medicaid Statistical Information System (formerly MedStat) |
| MSIS | Multiple Sclerosis Impact Scale |
| MSIS | Meldingssystem for Smittsomme Sykdommer (Norwegian: Communicable Diseases Registry) |
| MSIS | Marine Safety Information System |
| MSIS | Man-Systems Integration Standards |
| MSIS | Mass Spectrometer and Incoherent Scatter |
| MSIS | Master of Science Information Systems |
| MSIS | Model State Information System (EPA) |
| MSIS | Modeling and Simulation Information System |
| MSIS | Malawi Social Indicator Survey |
| MSIS | Master of Spatial Information Science |