| Acronym | Definition |
|---|
| MSL | Moisture Sensitivity Level |
| MSL | Mars Science Laboratory |
| MSL | Mean Sea Level |
| MSL | Missile |
| MSL | Martin St. Louis (hockey player) |
| MSL | Medical Science Liaison |
| MSL | Maine State Library |
| MSL | Maximum Segment Lifetime |
| MSL | Martha Stewart Living |
| MSL | Media Services Limited (various locations) |
| MSL | Michael Smith Laboratories (Canada) |
| MSL | Minimum Standard of Living |
| MSL | Master Symbol List |
| MSL | Microsoft Licenses |
| MSL | Meridian Switch Load |
| MSL | Mobile Station Location |
| MSL | Microsoft Software Library |
| MSL | Microsoft Learning |
| MSL | Machine Status Link |
| MSL | Multi Site License |
| MSL | Midstage Access Loss |
| MSL | Multi Single Level |
| MSL | Managed System List |
| MSL | Midrange Storage Library |
| MSL | Magic Scripting Language |
| MSL | Multi-Site License (software contracts) |
| MSL | Mexican Sign Language |
| MSL | Manning Selvage & Lee (New York, NY) |
| MSL | Microgravity Science Laboratory |
| MSL | Minimum Stock Level (inventory) |
| MSL | Measles |
| MSL | Materials Science Laboratory |
| MSL | Mirrored Server Link |
| MSL | Mission and Spacecraft Library (US NASA) |
| MSL | Military Shipping Label |
| MSL | Minimum Salary Level (various locations) |
| MSL | Major Soccer League |
| MSL | Microsoft Support Lifecycle |
| MSL | Meters above Sea Level |
| MSL | Main Street Landing (Burlington, VT) |
| MSL | Master of Science in Leadership (various universities) |
| MSL | Measurement and Standards Laboratories (National Institute of Standards & Technology) |
| MSL | Market Supply Logistics |
| MSL | Master Subsidy Lock |
| MSL | Mission Simulation |
| MSL | Mean Sleep Latency |
| MSL | Mechanical System Laboratory (Combat Vehicles Research and Development Establishment; India) |
| MSL | Map Specification Library |
| MSL | Maximum Segment Life (TCP networking) |
| MSL | mIRC Scripting Language |
| MSL | Multiple Security Levels |
| MSL | Master of Studies in Law Degree |
| MSL | Model Schema Language |
| MSL | Micro Spherical Log (drilling) |
| MSL | Modify System Logging |
| MSL | Muscle Shoals / Florence / Sheffield, AL, USA - Muscle Shoals (Airport Code) |
| MSL | Midsternal Line |
| MSL | Main Steam Line |
| MSL | Marine Safety Laboratory (US Coast Guard) |
| MSL | Minimum Subsistence Level |
| MSL | Micro-Strip Line |
| MSL | Master Station Log |
| MSL | Mapping Specialists, Ltd. (Fitchburg, WI) |
| MSL | Maximum Securing Load |
| MSL | Mouvement Social Libanais (French) |
| MSL | MBCGame Star League (video game tournament; Korea) |
| MSL | Mercy School of Law (University of Detroit) |
| MSL | Maintenance Supply Liaison |
| MSL | My Sweet Love |
| MSL | Master Support List |
| MSL | Missouri Synod Lutheran |
| MSL | Minimum Staffing Level |
| MSL | Minimum Spending Level |
| MSL | Mid Stage Loss (insertion loss between two stages of an optical amplifier) |
| MSL | Multipoint Service Legs |
| MSL | Management System Laboratory |
| MSL | Material Support List |
| MSL | Master Software Library |
| MSL | Maritime Security Line |
| MSL | Medical Staff Line (software from Healthline Systems) |
| MSL | Multi Sensory Language |
| MSL | Minesweeper, Launch |
| MSL | Minimum Sensitivity Level |
| MSL | Maximum Stress Load |
| MSL | Managed Service Leads |
| MSL | Microstereo Lithography |
| MSL | Minimum Sustained Load |
| MSL | Member of the Order of St. Lazarus |
| MSL | Multistation Localization |
| MSL | Medium Split Lockwasher |
| MSL | Must Sell Listings |
| MSL | Merrett Syndicates Ltd |
| MSL | Mobile Software Laboratory (DoCoMo) |