| Acronym | Definition |
|---|
| NYC | New York City (New York, USA airport code) |
| NYC | New York Central (railroad) |
| NYC | New York Cares |
| NYC | New York Color |
| NYC | No You Can't |
| NYC | National Youth Council (Singapore) |
| NYC | Newport Yacht Club (various locations) |
| NYC | National Youth Commission |
| NYC | New York Collegium (Baroque music) |
| NYC | National Youth Conference (Church of the Brethren conference for high school youth) |
| NYC | National Youth Choir |
| NYC | Nacido Y Criado (Spanish: Born and Raised) |
| NYC | Nantucket Yacht Club (Nantucket, MA) |
| NYC | Nazarene Youth Conference |
| NYC | Nanaimo Yacht Club (Naniamo, BC, Canada) |
| NYC | North York City (center; Ontario, Canada) |
| NYC | National Youth Connection |