| Acronym | Definition |
|---|
| MSSE | Medicine & Science in Sports & Exercise |
| MSSE | Microsoft Security Essentials (computer software) |
| MSSE | Mini-Suffering State Examination (scale) |
| MSSE | Math, Science and Special Education (various locations) |
| MSSE | Ministry of Social Security and Employment (Portugal) |
| MSSE | Master of Science in Software Engineering |
| MSSE | Microsoft Search Server Express (software) |
| MSSE | Multiple Self-Healing Squamous Epithelioma |
| MSSE | Message Submission Service Element |
| MSSE | Micro and Small Scale Entrepreneurship |
| MSSE | methicillin-sensitive Staphylococcus epidermidis |
| MSSE | Master of Science in Secondary Education (Rochester Institute of Technology and State University of New York) |
| MSSE | Mobile Shared Spectrum Enabler |
| MSSE | Marine Safety Specialist Engineering (US Coast Guard) |
| MSSE | Market and Social Systems Engineering (lecture series) |