| Acronym | Definition |
|---|
| PGL | Graphics (File Name Extension) |
| PGL | Persistent Generalized Lymphadenopathy (associated with HIV AIDS viral infection) |
| PGL | Pro Gaming League (Canada) |
| PGL | Professional Gamers League |
| PGL | Portable Graphics Library |
| PGL | Policy Guidance Letter |
| PGL | Portable Game Library |
| PGL | Peer Group Leader |
| PGL | Pokemon Global Link |
| PGL | Publishing Group Ltd. (various locations) |
| PGL | 6-@phosphogluconolactonase (deficiency) |
| PGL | Parents Get Lost (UK summer camps) |
| PGL | Printronix Graphics Language (printers) |
| PGL | Peer Group Leader (Sprint) |
| PGL | Plasma Glucose Level |
| PGL | Peoples Energy Corporation (stock symbol) |
| PGL | Peter Gordon Lawrence (UK childrens' holiday company) |
| PGL | Practice Group Leader |
| PGL | Professional Gaming League |
| PGL | Pulse Generating Laser (ERGO) |
| PGL | Paragangliomata |
| PGL | Projective General Linear (mathematics) |
| PGL | Paraganglioma Syndrome |
| PGL | Program Guidance Letter |
| PGL | Profile Grade Line |
| PGL | Promina Group Limited (insurance; Australia and New Zealand) |
| PGL | PreGame Lobby |
| PGL | Pakistan Gaming League (computer gaming association) |