| Acronym | Definition |
|---|
| PGO | Profile-Guided Optimization (computer programming) |
| PGO | Plan Gospodarki Odpadami (Polish: Waste Management Plan) |
| PGO | Prevot Gilles and Olivier |
| PGO | Profile Guided Optimization |
| PGO | Pistol Grip Only (shotguns) |
| PGO | Public Guardianship Office (UK) |
| PGO | Ponto-Geniculo Occipital (burst neurons) |
| PGO | Post-Grant Opposition (intellectual property; various locations) |
| PGO | Pass Grade Only (academics) |
| PGO | Project on Government Oversight |
| PGO | Particuliere Gegevensbeherende Organistatie |
| PGO | Policy, Guidance and Oversight |
| PGO | Project GNOME Organization (US Atomic Energy Commission) |