| Acronym | Definition |
|---|
| OPN | Oneohtrix Point Never (recording alias) |
| OPN | Ora Pro Nobis (Latin: Pray for Us) |
| OPN | Open |
| OPN | Osteopontin (protein) |
| OPN | Optics & Photonics News (Optical Society of America) |
| OPN | Oracle PartnerNetwork |
| OPN | Ojcowskiego Parku Narodowego (Polish: Paternal National Park) |
| OPN | Open Partial Nephrectomy |
| OPN | Outrage Performance Monitoring |
| OPN | Office Productivity Network |
| OPN | Open Projects Network |
| OPN | Oracle Partner Network |
| OPN | Open Presence Network |
| OPN | Ordering Part Numbers |
| OPN | Ordering Part Number |
| OPN | Ojcowski Park Narodowy (Polish: Ojców National Park) |
| OPN | Other Procurement, Navy |
| OPN | Open Projects Network (IRC Network) |
| OPN | On Purpose Networking (Ginny Robertson) |
| OPN | Orderable Part Number |
| OPN | Optical Packet Node |
| OPN | Operational Processing Centers |
| OPN | Open Parlor Night |