| Acronym | Definition |
|---|
| PICO | Program in Chip Out |
| PICO | PINE Composer |
| PICO | Pacific Institute for Community Organization (Oakland, CA) |
| PICO | People Improving Communities through Organizing (est. 1972) |
| PICO | Polar Ice Coring Office |
| PICO | Polio Information Center Online |
| PICO | Program In, Chip Out (Hewlett-Packard Development Company, LP) |
| PICO | Patient/Problem, Intervention, Comparison, Outcome (evidence-based medicine) |
| PICO | Pervasive Information Community Organization |
| PICO | Power Integrity Corporation |
| PICO | Pre-Installation Check Out (equipment component testing prior to delivery) |
| PICO | port in charterers option |
| PICO | Plant Improvement Company Ltd (Okanagan Plant Improvement Corporation; Summerland, BC, Canada) |
| PICO | Product Improvement Control Office |