| Acronym | Definition |
|---|
| OPSC | Office of Public School Construction |
| OPSC | Oregon Plumbing Specialty Code |
| OPSC | Orissa Public Service Commission (India) |
| OPSC | Osteopathic Physicians and Surgeons of California |
| OPSC | Office of the Public Service Commissioner (Queensland, Australia) |
| OPSC | Outpatient Surgical Center (various locations) |
| OPSC | Oregon Patient Safety Commission (est. 2003) |
| OPSC | Orland Park Soccer Club (Orland Park, IL) |
| OPSC | Optional Protocol on Sale of Children, Child Prostitution, and Child Pornography (UN Convention on the Rights of the Child; UN Children's Fund) |
| OPSC | Ohio Public Service Company |
| OPSC | Oregon Plumbing Safety Code (laws) |