| Acronym | Definition |
|---|
| OSN | Orbit Showtime Network (TV service; United Arab Emirates) |
| OSN | Ocular Surgery News |
| OSN | Open Source Network |
| OSN | Osa Network |
| OSN | Office System Node |
| OSN | Optical Service Network |
| OSN | Open Storage Networking |
| OSN | Open Systems Network |
| OSN | Open Space Network |
| OSN | Open Solution Network |
| OSN | Output Sequence Number |
| OSN | Optical Service Node |
| OSN | Ontario Stroke Network (cardiology; Ontario, Canada) |
| OSN | Orquesta Sinfónica Nacional (Spanish: National Symphony Orchestra; Mexico) |
| OSN | Oregon Sports Network |
| OSN | Oracle Social Network (software) |
| OSN | Onion Sports Network (satirical news) |
| OSN | Office of Special Needs |
| OSN | Online Social Network |
| OSN | Obras Sanitarias de la Nación (Argentina) |
| OSN | Output Sequence Number (SWIFT) |
| OSN | Open Services Networking (various companies) |
| OSN | Oklahoma Sustainability Network (Oklahoma City, OK) |
| OSN | Organic Solvent Nanofiltration |
| OSN | On Sale Now |
| OSN | Organizace Spojených Národù (Czech) |
| OSN | One Stop Notification |
| OSN | Open Software Network |
| OSN | Oracle Supplier Network (Austin, TX) |
| OSN | Overlay Service Network |
| OSN | Office of the Secretary of the Navy |
| OSN | Operations Support Network (Ericsson) |
| OSN | Old Sinful Nature |
| OSN | Open Studios Network (UK) |
| OSN | Optical Star Network |
| OSN | Output Sub-Node |
| OSN | Order of St. Nicholas |
| OSN | On-demand Secure Network |
| OSN | Organ-Specific Neoantigen |
| OSN | operating system neutrality |
| OSN | Optical Service Network(s) (fiber optics) |