| Acronym | Definition |
|---|
| PY | Python (file format/extension) |
| PY | Paraguay (IAO country code, top level domain) |
| PY | Program Year |
| PY | Polygon |
| PY | Spray (METAR obscuration) |
| PY | Pyridine (chemistry) |
| PY | Poka Yoke (Japanese: Mistake Proofing) |
| PY | Prior Year |
| PY | Planning Yard (US Navy) |
| PY | Part Year |
| PY | PangYa (MMO game) |
| PY | Project Yes (various organizations) |
| PY | Pete Yorn (musician) |
| PY | Payroll Accounting |
| PY | Personnel Year (education) |
| PY | Patient Year |
| PY | Physical Year |
| PY | Phoenix Yellow (Acura Integra Type R color) |
| PY | Planning Year |
| PY | Promotion Year |
| PY | Patrol Vessel, Yacht (US Navy) |
| PY | Surinam Airways Ltd (IATA airline code) |