| Acronym | Definition |
|---|
| APPLE | Apple Pugetsound Program Library Exchange (user group) |
| APPLE | Ariane Passenger Payload Experiment |
| APPLE | Alliance for a Post-Petroleum Local Economy (California) |
| APPLE | Accredited Professional Preschool Learning Environment (Fort Myers, FL) |
| APPLE | Área de Paisagem Protegida do Litoral de Esposende (Portugal) |
| APPLE | Aids Prevention Plus Life Education (est. 2001; Zambia) |
| APPLE | All Punks Please Leave Earth (band) |
| APPLE | A Personal Path to Lifelong Education (Colton, CA) |
| APPLE | Apple and Pear Product Liaison Executive (CAMRA group to promote cider and perry) |
| APPLE | Association to Promote and Protect the Lubec Environment (Maine) |
| APPLE | Ask, Pause, Pick, Listen, Evaluate |
| APPLE | Apollo Payload Exploration |