OPSU
| Acronym | Definition |
|---|---|
| OPSU | Oklahoma Panhandle State University (Goodwell, Oklahoma) |
| OPSU | Oil Pressure Sending Unit (car engine part) |
| OPSU | Olympic Programme Support Unit (UK) |
| OPSU | Olympic Peninsula Sports Union (Bremerton, WA) |
| OPSU | Operational Process and Support Unit (UK) |
| OPSU | Onboard Power Supply Unit (nuclear weapons) |