| Acronym | Definition |
|---|
| OSO | Oxford Scholarship Online (UK) |
| OSO | Om Shanti Om (Bollywood movie) |
| OSO | Object Space Object |
| OSO | Originating Signaling Office |
| OSO | over Scan Operation |
| OSO | Online Sales and Operations (Google team) |
| OSO | Orbiting Solar Observatory |
| OSO | On-Screen Orgasm |
| OSO | Office of Satellite Operations (US Department of Commerce, NOAA) |
| OSO | Onsala Space Observatory |
| OSO | Oregon State Office |
| OSO | One-Stop Operator (various locations) |
| OSO | Occupational Safety Officer (various organizations) |
| OSO | Office of Strategic Operations (fiction) |
| OSO | Officer Selection Office |
| OSO | Office of Systems Operations (Social Security Administration) |
| OSO | Office of Systems Operations (NOAA, Silver Spring, MD) |
| OSO | Ottawa Symphony Orchestra (Canada) |
| OSO | Operational Support Office |
| OSO | Office of Security Operations |
| OSO | Office of Space Operations (NASA) |
| OSO | OverScan Operation (VXA Technology) |
| OSO | Offensive Systems Operator |
| OSO | Ontario Special Olympics (Canada) |
| OSO | Other Significant Other |
| OSO | Ostsüdost (German: East-South-East) |
| OSO | Office of SIGINT Operations |
| OSO | Ovest-Sud-Ovest (Italian: West-South-West) |
| OSO | Order Sending Organization (NASD) |
| OSO | Osoboe Sovescanie Special Commission (Soviet Union, Communism, Stalin) |
| OSO | Operations Staff Officer |
| OSO | Other Supply Officer |
| OSO | Ordnance Supply Office |
| OSO | Organizational Security Officer |
| OSO | Oxfordshire Schools Orchestra (UK) |
| OSO | Objectives & Strategies Overview |
| OSO | Ordnance Safety Observer |
| OSO | Office of Signals Operations (US CIA) |