| Acronym | Definition |
|---|
| PRU | Prudential Financial |
| PRU | Pupil Referral Unit |
| PRU | Programmable Real-Time Unit |
| PRU | Port Replacement Unit |
| PRU | Platelet Reactivity Unit |
| PRU | Photographic Reconnaissance Unit |
| PRU | Potomac Rugby Union (Washington, DC) |
| PRU | Provincial Reconnaissance Unit |
| PRU | Projets de Rénovation Urbaine |
| PRU | Primary Reporting Unit (US DoD) |
| PRU | Pararescue Unit (US DoD) |
| PRU | Pruhonice (seismological station) |
| PRU | Photo-Reconnaissance Unit |
| PRU | Processor Unit |
| PRU | Public Relations Unit |
| PRU | Poverty Research Unit (University of Sussex) |
| PRU | Program Review Unit (various organizations) |
| PRU | Plant Research Unit |
| PRU | Population Research Unit |
| PRU | Patient Referral Unit (psychiatric) |
| PRU | Peripheral Resistance Unit |
| PRU | Pseudo-Random Upstream (Sequence) |
| PRU | Packet Radio Unit (Digital Battlestaff Sustainment Trainer) |
| PRU | POGO Research Unit |
| PRU | Personnel Readiness Unit |
| PRU | Pay Research Unit (United Kingdom) |
| PRU | Programme de Réparations d'Urgences |
| PRU | Palestine Research Unit |
| PRU | Photosynthesis Research Unit |
| PRU | Poultry Research Unit (Glasgow University Veterinary School) |
| PRU | Plate Recognition Unit |
| PRU | Personal Recording Unit |
| PRU | Power Regulation Unit |
| PRU | Plastics Recycling Update |
| PRU | Pediatric Rehabilitation Unit (Kennedy Krieger Institute) |
| PRU | Passavant Roediger Umvelttechnik GmbH |
| PRU | Poison Reverse Update |
| PRU | Program Resources Unit |
| PRU | Partially Row Uniform |
| PRU | Portable Replay Unit |
| PRU | Production Representative Unit |
| PRU | Power Rectifier Unit |
| PRU | Paleoenvironmental Research Unit (National University of Ireland, Galway) |