| Acronym | Definition |
|---|
| PCSC | Personal Computing Support Center |
| PCSC | Personal Computer Smart Card |
| PCSC | President Chain Store Corporation (Taiwan) |
| PCSC | Preventing and Combating Serious Crime (international agreement) |
| PCSC | Personal Computer / Smart Card |
| PCSC | pricing and classification service center (US Postal Service assistance facility) |
| PCSC | Police Civil Service Commission (various locations) |
| PCSC | Parts Canada Superbike Championship (racing) |
| PCSC | Pacific Coast Steamship Company (est. 1882) |
| PCSC | Personal Communications Switching Center |
| PCSC | Pontifical Council for Social Communications |
| PCSC | Preliminary Certificate in Social Care (UK) |
| PCSC | Personal Computer Site Coordinator |
| PCSC | Program Change Sub-Committee |
| PCSC | private child support collector |
| PCSC | Professional Certificate in Specialty Construction |