| Acronym | Definition |
|---|
| PHE | Public Health England (UK) |
| PHE | Phenylalanine (Amino Acid) |
| PHE | Protection of the Human Environment (World Health Organization) |
| PHE | Paramount Home Entertainment (Viacom, Inc.) |
| PHE | Pathway to Higher Education |
| PHE | Plate Heat Exchanger (mechanical engineering) |
| PHE | Public Health Expenditure |
| PHE | Padlock Hash Engine |
| PHE | Protocol Header Encryption |
| PHE | Public Health Engineering |
| PHE | Population Health and Environment |
| PHE | Periodic Health Examination (wellness; Canada) |
| PHE | Preventive Health Exam (healthcare) |
| PHE | Prosecution History Estoppel |
| PHE | Plastic High Explosive |
| PHE | Port Hedland, Western Australia, Australia - Port Hedlan (Airport Code) |
| PHE | Proliferative Hemorrhagic Enteropathy (pig disease) |
| PHE | Philadelphia Handbell Ensemble (Pennsylvania) |
| PHE | Propellant Handling Unit |