| Acronym | Definition |
|---|
| POF | Plenty of Fish (dating website) |
| POF | Path of Fire (gaming, Guild Wars 2) |
| POF | Plastic Optical Fiber |
| POF | Privilege of the Floor (political speeches) |
| POF | Philosophy of Freedom |
| POF | Point of Fire |
| POF | Premature Ovarian Failure (early menopause) |
| POF | Power of the Force (Star Wars movie) |
| POF | Pattern of Failure (oncology) |
| POF | Piano dell'Offerta Formativa (Italian school document) |
| POF | People over Fifty (various organizations) |
| POF | Physics of Fluids (American Institute of Physics) |
| POF | Proof of Funds |
| POF | Pretty on Fleek (music) |
| POF | Plenty of Freaks |
| POF | Pay on Foot (parking) |
| POF | Programmable Operator Facility |
| POF | Print Order Format |
| POF | Print Object File |
| POF | Programmer Object File |
| POF | Portable Object Format |
| POF | Phone Offline |
| POF | Palm Oil Free |
| POF | Polymer Optical Fiber |
| POF | Physics-Of-Failure |
| POF | Planes of Fame (air museum at Chino Airport, California) |
| POF | Proof of Feasibility (drug manufacturing) |
| POF | Probability of Failure |
| POF | Pakistan Ordnance Factory |
| POF | Point of Failure |
| POF | Plenty of Fakers |
| POF | Priority of Fires (US DoD) |
| POF | Philippine Olympic Festival |
| POF | Plane of Fear (gaming) |
| POF | Plane of Focus (photography) |
| POF | Purchase Order Financing |
| POF | Pillar of Fire (church in Denver, CO, USA) |
| POF | PowerOn Fusion (software community) |
| POF | Phase Only Filter |
| POF | Permanent Operations Facility |
| POF | Perfect Order Fulfillment |
| POF | Payment for Order Flow (stock exchange) |
| POF | Pieces of Flair (blog) |
| POF | Pontificating Old Fart |
| POF | Patient's Own Frame |
| POF | Private Operating Frequencies |
| POF | Pot of Food (fire service members) |
| POF | Pulse Outline Format |
| POF | Permanently Oil Filled |
| POF | Put on File |
| POF | Period of Affordability |