| Acronym | Definition |
|---|
| PRISMS | Princeton International School of Mathematics and Science (Princeton, NJ) |
| PRISMS | Provider Registration and International Students Management System (Department of Education, Employment and Workplace Relations; Australia) |
| PRISMS | Parents and Researchers Interested in Smith-Magenis Syndrome (est. 1993; Sterling, VA) |
| PRISMS | Program Information Systems Mission Services (NASA contract) |
| PRISMS | Prevention Risk Indicator/Services Monitoring System (Office of Alcoholism and Substance Abuse Services; New York) |
| PRISMS | Pilot/Rotorcraft Intelligent Symbology Management Simulator (virtual reality simulation tool) |
| PRISMS | Physics Resources and Instructional Strategies for Motivating Students Project (University of Northern Iowa; Cedar Falls, IA) |