| Acronym | Definition |
|---|
| PDE | Personal Development Education |
| PDE | Pennsylvania Department of Education |
| PDE | Provincial Department of Education (various locations) |
| PDE | Partial Differential Equation |
| PDE | Professional Development & Education (various organizations) |
| PDE | Pengolahan Data Elektronik (Indonesian: Electronic Data Processing) |
| PDE | Product Development Engineer (various companies) |
| PDE | Probability Density Estimation (physics) |
| PDE | Processing Development Environment (software) |
| PDE | Phosphodiesterases |
| PDE | Power Distribution Equipment (est. 1997; Franklin Park, IL) |
| PDE | Phi Delta Epsilon (medical fraternity) |
| PDE | Plug-In Development Environment |
| PDE | Permitted Daily Exposure |
| PDE | Personal Developer'S Edition |
| PDE | Position Determination Entity |
| PDE | Possible Duplicate Emission |
| PDE | Pulse Detonation Engine |
| PDE | Panama Diamond Exchange (Panama City, Panama) |
| PDE | Planning, Decision, and Execution |
| PDE | Paramount Digital Entertainment |
| PDE | Plataforma en Defensa de l'Ebre (Catalan: Platform for the Defence of the River Ebre) |
| PDE | Paul Dresher Ensemble (Brooklyn, NY) |
| PDE | Personal Digital Entertainment |
| PDE | Prescription Drug Event |
| PDE | Product Data Exchange |
| PDE | Present-Day English |
| PDE | Professional Development Event |
| PDE | Print Data Exchange (Japan) |
| PDE | Project Dive Exploration (Divers Alert Network) |
| PDE | Purely Domestic Enterprise (finance) |
| PDE | Position Determining Entity |
| PDE | Photon Detection Efficiency |
| PDE | Primary Developmental Education (US Air Force) |
| PDE | Plataforma en Defensa del Ebro (Spanish: Platform for the Defence of the River Ebre) |
| PDE | Pseudo Death Experience |
| PDE | Project Development Engineer |
| PDE | Portable Electronic Device |
| PDE | Product Design Engineer |
| PDE | Pyridoxine-Dependent Epilepsy |
| PDE | Primary Designated Engineer |
| PDE | Process Development Engineer |
| PDE | Primark Decision Economics |
| PDE | Production Estimate |
| PDE | Potential Daily Exposure |
| PDE | Philadelphia Drug Exchange |
| PDE | Projected Operational Environment |
| PDE | Propagation Delay Estimation |
| PDE | Pre-Emphasis/De-Emphasis |
| PDE | Preliminary Determination of Epicenter(s) (USGS) |
| PDE | Paddle Drive Electronics |
| PDE | Preliminary Data Element |
| PDE | Project/Program Director, Electronics |
| PDE | Permission Display Engine |
| PDE | Predictive Density Estimation |