| Acronym | Definition |
|---|
| OPW | Office of Public Works (Ireland) |
| OPW | Online Personals Watch (est. 2004; online dating) |
| OPW | Organization Plus for Windows |
| OPW | Office Profile Wizard |
| OPW | Outreach Program for Women (various organizations) |
| OPW | Orthogonalized Plane Wave |
| OPW | Open Pilot Warranty (insurance) |
| OPW | Off Premise Worker (Cisco) |
| OPW | Operational Planning Worksheet (US FEMA) |
| OPW | Other People's Wives |
| OPW | Objective Personal Weapon |
| OPW | Ohio Pattern Works |
| OPW | One Peaceful World (journal) |
| OPW | Outline Plan of Works (New Zealand) |
| OPW | Oldest Packet Win (throughput scheme) |