| Acronym | Definition |
|---|
| OWC | Officers' Wives' Club |
| OWC | Other World Computing (retail store) |
| OWC | Organic World Congress (agriculture) |
| OWC | Office Web Components |
| OWC | Osu! World Cup |
| OWC | Oracle Web Center |
| OWC | Office of Web Consultation |
| OWC | Optical Wheel Mouse |
| OWC | Oracle Web Conferencing |
| OWC | Open Web Center |
| OWC | Optimal Wellness Center (various locations) |
| OWC | Oscillating Water Column |
| OWC | Orange Watch Company (Australia) |
| OWC | Owner Will Carry (real estate owner will carry mortgage) |
| OWC | Okaloosa-Walton College |
| OWC | Office of Workers' Compensation |
| OWC | Oil Water Contact (oil industry) |
| OWC | Oracle Web Conference |
| OWC | Original Wooden Case (wine collectors) |
| OWC | One Way Container (shipping) |
| OWC | Optimal Water Content (engineering) |
| OWC | Oklahoma Wheat Commission |
| OWC | Our Wee Country (Northern Ireland) |
| OWC | Operating Working Capital |
| OWC | Ocean Wildlife Campaign |
| OWC | One-Way Communication |
| OWC | Operational Working Capital (economics) |
| OWC | Oregon Wheat Commission |
| OWC | Owning Work Center (USAF) |
| OWC | Operational Watch Commander (US Navy) |
| OWC | Open with Care |
| OWC | Outwit Catch (file extension) |
| OWC | Open Watershed Conservation |
| OWC | Obstacle Warning Cue |