| Acronym | Definition |
|---|
| OTW | Over the Weekend (blog) |
| OTW | Out of This World (various organizations) |
| OTW | Otherwise |
| OTW | Of The World (online TV network) |
| OTW | Off The Wall |
| OTW | On the Way |
| OTW | On The Web |
| OTW | Open the Web (software) |
| OTW | Over the World |
| OTW | On The Water (rowing term for the start of a session) |
| OTW | On the Whole |
| OTW | Over-The-Wire |
| OTW | Out the Window (display/graphics) |
| OTW | Off-Track Wagering |
| OTW | Over The Wall |
| OTW | Organization for Transformative Works |
| OTW | Outside the Wire |
| OTW | Overtime Win (hockey) |
| OTW | One Time Watch (movies) |
| OTW | One to Watch |
| OTW | Old Time Wrestling |
| OTW | Over the Water |
| OTW | Off the Wagon |
| OTW | Other Than War |
| OTW | On the Wagon (alcohol abstinence) |
| OTW | One True Way |
| OTW | Off To War |
| OTW | Of The Whale (gaming, World of Warcraft) |
| OTW | Oceanic Time Warner (Hawaii cable TV) |
| OTW | Oldham Theatre Workshop (UK) |
| OTW | Order to Withhold (California Franchise Tax Board) |
| OTW | One Train Working |
| OTW | One-Time Waiver |
| OTW | Orlando Tech Works, LLC (Orlando, Florida) |
| OTW | Oudtestamentisch Werkgezelschap in Nederland en België (Old Testament study society) |
| OTW | Optimal Transmit Weight |