| Acronym | Definition |
|---|
| SIGMA | Software Industrialized Generation and Maintenance Aids |
| SIGMA | Sign and Mac |
| SIGMA | Society of Independent Gasoline Marketers of America |
| SIGMA | Support for Improvement in Governance and Management (EU, OECD) |
| SIGMA | Sealed Insulating Glass Manufacturers Association |
| SIGMA | Système d'Imagerie Gamma à Masque Alèatoire (French: Random Gamma Imaging System Mask) |
| SIGMA | Socio-Sexual Investigations of Gay Men and Aids (longitudinal study, England and Wales) |
| SIGMA | Science de l’Information Géoréférencée pour la Maîtrise de l’environnement et l’Aménagement des territoires |
| SIGMA | Simulation Guided Memory Analyzer |
| SIGMA | Sediment Identification for Geotechnics by Marine Acoustics |
| SIGMA | Sequential Information Gathering in Machines and Animals |
| SIGMA | Special Interest Group on Multimedia/Medical Applications |
| SIGMA | Gas-Particle Interactions in a Microgravity Flow Cell |
| SIGMA | Software Industrialized Generator & Maintenance Aids |
| SIGMA | Site Information Generation & Materiel Accountability Plan |
| SIGMA | Strategic Information for Global Markets in Agrochemicals |
| SIGMA | Student Information & Grades Management Application (University of British Columbia; Vancouver, BC, Canada) |