| Acronym | Definition |
|---|
| POSS | Polyhedral Oligomeric Silsesquioxanes |
| POSS | Point of Sale Software (various organizations) |
| POSS | Palomar Observatory Sky Survey |
| POSS | Point of Sale Subsystem |
| POSS | Plant Operator Selection System |
| POSS | Project of State Significance (Tasmania, Australia) |
| POSS | Point of Slope Selection |
| POSS | Precipitation Occurrence Sensor System |
| POSS | Puckett Observatory Supernova Search |
| POSS | Passive Optical Satellite Surveillance |
| POSS | Palm Operating System Simulator |
| POSS | Prototype Optical Surveillance System |
| POSS | Parallel Pair of Open-and Shorting-Stubs (microwave theory) |