| Acronym | Definition |
|---|
| PBL | Problem-Based Learning |
| PBL | Phi Beta Lambda |
| PBL | Performance Based Logistics |
| PBL | Peripheral Blood Lymphocyte (blood cells) |
| PBL | Planbureau voor de Leefomgeving (Dutch: Planning for the Environment; Netherlands Environmental Assessment Agency) |
| PBL | Points, Badges, and Leaderboards (gaming) |
| PBL | Planetary Boundary Layer |
| PBL | Protected Bike Lane (various locations) |
| PBL | Philippine Basketball League |
| PBL | Put Block |
| PBL | Primary Boot Loader |
| PBL | Power Basic Library |
| PBL | Performance-Based Leadership |
| PBL | Publishing and Broadcasting Limited (Australia) |
| PBL | Peripheral Blood Leukocyte |
| PBL | Panacea Biotec Ltd. (India) |
| PBL | Primary Boot Loader (computing) |
| PBL | Product Baseline |
| PBL | Problem/Project Based Learning |
| PBL | Project-Based Lesson (education) |
| PBL | Pacific Brands Ltd. (Australia) |
| PBL | Policy Based Loan |
| PBL | Philadelphia Belt Line Railroad |
| PBL | Polish Peasant Bloc |
| PBL | Patrol Boat Light (US Navy) |
| PBL | Policy By-Laws (Australian government) |
| PBL | Protection Ballistic Limit |
| PBL | Power Builder Library |
| PBL | Points Behind Leader (hockey) |
| PBL | Per Beneficiary Limit |
| PBL | Poly Buffer LOCOS (Local Oxidation of Silicon) |
| PBL | Policy Blocking List (SPAM filtering) |
| PBL | Project By-Law (Australia) |
| PBL | Punishable By Life imprisonment (Florida) |
| PBL | Plastic Barrier Layer (soft goods packaging) |
| PBL | Peanut Butter Legs |
| PBL | Phrase-Based Language (speech synthesis development tool) |
| PBL | Pay by the Load (transportation) |
| PBL | Persons, Behle and Latimer (law firm) |