| Acronym | Definition |
|---|
| PBU | Philadelphia Biblical University (Langhorn, PA) |
| PBU | Proxy Binding Update (mobile communications) |
| PBU | Pass Break Up (football) |
| PBU | Predominantly Black University |
| PBU | Previously Banned User (forums) |
| PBU | Pressure Build-Up |
| PBU | Polimorfismo de Base Unica (Spanish: Single Nucleotide Polymorphism) |
| PBU | Producer Business Unit |
| PBU | Partys-Bei-Uns (Partys-by-us) |
| PBU | Passenger Business Unit |
| PBU | Periodic Building Unit |
| PBU | PaintBallersUnit |
| PBU | Photo Blow-Up |
| PBU | Period of Beneficial Use |
| PBU | Premature Babies Unit |
| PBU | Project Barito Ulu (Cambridge University; UK) |