| Acronym | Definition |
|---|
| PUMA | Party Unity My Ass (US politics) |
| PUMA | Personal Urban Mobility and Accessibility (electric vehicle development) |
| PUMA | Purple Martin (bird species) |
| PUMA | Protected User Mode Audio |
| PUMA | Power User'S Macintosh Application |
| PUMA | Public Use Microdata Area (US Census) |
| PUMA | Programa Universitario del Medio Ambiente (Spanish: Academic Environmental Program; Mexico) |
| PUMA | Propagating Uncertainty in Microarray Analysis |
| PUMA | Please Use More Acronyms |
| PUMA | Protected User Mode Audio (Microsoft) |
| PUMA | Programmable Universal Machine for Assembly |
| PUMA | Pascal Units for Medical Applications (medical informatics) |
| PUMA | Power User's Macintosh Association |
| PUMA | Processor Upgradable Modular Architecture |
| PUMA | Physician Utilization Management Advisor (various organizations) |
| PUMA | Precision Underwater Mapping |
| PUMA | Pennsylvania United Medical Association (Penndel, PA) |
| PUMA | Processus Urbanisant les Méthodes Agiles (French: Urbanization Process Agile Methods) |
| PUMA | Parallel Universal Message Passing Architecture |
| PUMA | Prostitutes Union of Massachusetts |
| PUMA | Periscope Mirror |
| PUMA | Polyurethane Methyl Acrylate |
| PUMA | PowerPC Ultrafast Multi-chip module Architecture |