| Acronym | Definition |
|---|
| OPF | Order Processing Fee (sales) |
| OPF | Operation Flashpoint (game) |
| OPF | Onshore Processing Facility |
| OPF | OPEN Process Framework |
| OPF | Overseer Plug-in File |
| OPF | Official Personnel Folder |
| OPF | Orbiter Processing Facility |
| OPF | Optimal Power Flow |
| OPF | Organizational Process Focus (Process Area; Capability Maturity Model Integration) |
| OPF | Overseas Pakistanis Foundation |
| OPF | Official Personnel File |
| OPF | Online Photo Filer (website development; various companies) |
| OPF | Outperform (finance) |
| OPF | One-Piece Flow |
| OPF | Object Persistent Framework |
| OPF | Organization Process Focus |
| OPF | One Piece Folder (corrugated box style) |
| OPF | Outpost of Freedom (political website) |
| OPF | Orange Prize for Fiction (UK) |
| OPF | Miami, FL, USA - Opa Locka (Airport Code) |
| OPF | Oil Protection Force (Iraq) |
| OPF | Open Photography Forum |
| OPF | Office Protestant de la Formation |
| OPF | Oil Palm Frond |
| OPF | Other People's Food |
| OPF | Onshore Production Facility (oil and gas) |
| OPF | Outer Planets Flagship (mission) |
| OPF | Organic Phase Fluid |
| OPF | Of Possible Futures (science fiction novel) |
| OPF | Office/Official Personnel Folder |
| OPF | Overseas Property Fund |
| OPF | Other Procurement Funding |
| OPF | One Percent Foundation (California) |
| OPF | Once per Facet (laser scanning) |